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by Gemma Davison

5 Best Vitamin B12 Tests 2023: Are You Deficient in B12?

5 Best Vitamin B12 Tests 2023: Are You Deficient in B12?

Do you often feel fatigued, foggy, and lethargic? Are you experiencing frequent digestive distress, vision loss, and nerve problems, such as muscle tingling or weakness? These are all symptoms of a vitamin B12 deficiency – which, if left untreated, is known to lead to anemia. So, it’s probably a good idea to take a vitamin B12 test to be on the safe side.

Even if you don’t think you’re deficient, optimizing your vitamin B12 levels can be beneficial if you’re thinking of becoming pregnant or you’re just not as young as you used to be.

You don’t need to wait for a potentially expensive doctor’s appointment as there is a wide selection of at-home Vitamin B12 tests that may save you time and money.

But how do you know which is the right vitamin B12 test for you? Which ones are accurate? Which will provide actionable insights and support if you are deficient?

Don’t worry – I’ve done the research for you, and found the best at-home vitamin B12 tests. My top choice is LetsGetChecked, as it’s reliable and accurate, and you get your results in just 2 to 5 days.

Check Your B12 Levels With LetsGetChecked!

Short on time? Here are our top picks for the best at-home vitamin B12 tests

  • LetsGetChecked’s test can identify a B12 deficiency in as little as five days.
  • Everlywell offers an affordable test for three key B vitamins, including vitamin B12
  • Living DNA determines how your genes may affect vitamin B12 absorption.

4 more great vitamin B tests | Check out our comparison table | FAQ

What We Look For in the Best Vitamin B12 Tests

We ensured that each vitamin B test met certain criteria to make it onto this list. Some may be more important for your needs than others, but they are all worth bearing in mind.

  • Actionability: Does your results report include personalized actionable insights, based on evidence? Is there expert support from a nutritionist or other health care provider?
  • Clarity: Are your results easy to understand? Is further explanation available if it’s required?
  • Value-for-money: Is the vitamin B12 test fairly priced? Do you have to pay for extras?
  • Trustworthiness: Is the test carried out in accredited labs? Are your results reviewed by physicians to ensure their accuracy? Does the company have a good standing with its customers?
  • Speedy Results: Do you receive your results quickly, so you can make any necessary changed or seek treatment as soon as possible.

1. LetsGetChecked – Accurate Individual Vitamin B12 Blood Test

  • At-home Vitamin B12 blood test
  • Medical support available to explain your results
  • Subscribe and save with regular testing
  • Results in 2-5 days

The individual Vitamin B12 test from LetsGetChecked uses a fingerprick blood sample to determine if you are suffering from a deficiency. A period of fasting is required before taking the test, and you should collect your blood sample before 9 am, returning it on the same day.

By testing your blood, the test measures your current B12 levels and if they are found to be too low, you can discuss your results and the next step with an experienced nurse.

Monitor your vitamin B12 levels and the impact of any lifestyle changes on your deficiency over time by subscribing to testing every three, six, or twelve months, and save up to 30%.

Get Started With LetsGetChecked!

2. Everlywell – Test Levels for Three Key B Vitamins

  • Blood test for three B vitamins
  • Actionable results in 3-5 days
  • Medical support available
  • Save money with an Everlywell membership

In addition to vitamin B12, the B Vitamins Test from Everlywell also tests your blood for your current B6 and B9 levels, which are also associated with fatigue and weakness.

The test can help identify deficiencies in these vitamins and determine if you need to make dietary changes to improve your overall health and wellness. Your easy-to-understand results include a personalized report for each B vitamin, as well as what the results mean for you. Plus, you’ll get guidance on how to improve or maintain healthy levels of these vitamins.

If you are concerned about chronic fatigue, Everlywell has other tests worth considering, including the Thyroid Test and Metabolism Test. However, we also strongly suggest you visit your healthcare provider, as the tests from Everlywell only provide an indicator of current levels of certain biomarkers, not a diagnosis.

Get the Best Everlywell Deal

3. Living DNA – Learn How Your Genes Affect Vitamin B12 Metabolism

  • Extensive nutrition DNA test
  • Analysis of genes associated with B12 absorption
  • Nutritional reports with diet recommendations
  • Results in 6-8 weeks

The Wellbeing Kit from Living DNA doesn’t test your levels of Vitamin B12. Instead, it analyzes genetic variants in your DNA that may affect vitamin B12 absorption. This can indicate if you’re genetically predisposed to a vitamin B12 deficiency.

You also get reports on how your unique genetic makeup can impact the way your body metabolizes other vitamins and minerals, influences blood glucose regulation, and omega-3 metabolism, as well as your predisposition to lactose intolerance and Celiac disease.

By understanding the role genetics plays in Vitamin B12 metabolism, you can take the necessary steps to optimize your levels. To help you, your Living DNA report includes tips on the foods that will provide you with the nutrients you need.

Get Started With Living DNA!

4. SelfDecode – Detailed Vitamin Reports

  • Analyzes genetic markers associated with B12 metabolism
  • Option to upload raw DNA data
  • Extensive personalized reports
  • Results in 6-8 weeks

SelfDecode uses your raw DNA data to flag genetic markers that are associated with B12 metabolism. Once you have submitted a DNA sample (either by saliva sample or existing DNA file), you can have it analyzed for certain genetic variations for personalized health reports.

A SelfDecode subscription allows you to claim a number of health reports for free, including the Vitamins DNA Wellness Report, which includes B12 and many others. Based on accurate information from the latest scientific studies, you get personalized recommendations based on your genetics to improve your levels.

The report provides an in-depth analysis of your B12 genetic profile and how your genetic variants might be affecting levels of the vitamin in your body. For example, the FUT2 and FUT6 genes protect the gut against H. pylori, a bacteria that can damage the stomach lining and reduce the protein required for B12 absorption. Plus FUT1 and FUT2 make the large intestine more hospitable to B12-producing bacteria.

With a SelfDecode subscription, you can use the Lab Test Analyzer Tool to decipher B12 lab tests and get personalized suggestions on how to achieve optimum levels to improve energy and motivation.

Get Started With SelfDecode Today!

5. Vitl – Check Current Levels & Genetic Predisposition

  • Affordable B12 blood and DNA tests
  • Actionable insights and personalized recommendations
  • Tailored supplement packages
  • Results in 2-3 weeks

Vitl offers both a DNA Vitamin Test to assess your predispositions to deficiencies and a Vitamin Blood Test to test your current vitamin levels.

The Vitamin DNA Test helps you to understand which vitamins and minerals – including B12 – you’re likely to have trouble absorbing or metabolizing, so you can make dietary changes to improve your levels.

Your results include a detailed genetic report along with personalized dietary and lifestyle advice to improve your wellbeing. Plus, there are additional insights such as if your vitamin B12 levels are likely to change during pregnancy.

The Vitamin and Cholesterol Blood Test measures your current Vitamin B12 levels (along with other things) and also provides personalized nutrition advice. With each test, you also have the option to purchase a supplement package tailored to your needs.

Get Your Vitl Test Today!

6. InsideTracker – Learn How to Optimize Your B12 Levels

  • Combined DNA and blood test
  • 2,000+ testing facilities across the US
  • Extensive personalized diet and nutrition advice.
  • Track your progress

Analysis of vitamin B12 is only available with InsideTracker’s Vitality and Ultimate plans, which are on the expensive side as they test for numerous other biomarkers, plus you’re required to travel to a testing facility to provide your blood sample.

If your results reveal your B12 levels are out of range (for your age, gender, and ethnicity), you’ll receive tailored dietary recommendations from a huge nutrition database of over 7,500 food items and hundreds of supplements.

You also have the option of uploading your data from past blood tests to see a more complete picture of your vitamin B12 levels over time.

Book Your InsideTracker Test Today!

7. GenePlanet – Vitamins and Minerals DNA Test

  • Affordable vitamin and minerals DNA test
  • Discover your genetic predispositions
  • Discuss your results with a nutrition specialist
  • Results in 2-4 weeks

The Vitamin and Mineral DNA test from Gene Planet analyzes over 10 micronutrients – including vitamin B12 – to determine your genetic predispositions for deficiencies and oxidative stress.

Your DNA is screened for unfavorable genetic variants of the FUT2 gene, which can reduce your levels of vitamin B12 by 10%. The least favorable outcome would be to have two copies of the gene, which would be 20% lower levels of B12.

The results reports include personalized recommendations to maintain better levels of micronutrients. Plus, you can discuss your results with a nutrition specialist during a free 30-minute consultation.

See The Best GenePlanet Deals!

What’s in the FinePrint?

I’ve researched each of the vitamin B12 tests thoroughly to ensure that you don’t get any nasty surprises, like extra costs.

There are no shipping costs forLetsGetChecked, Everlywell, orGenePlanet. Vitl also offers free delivery and prepaid postage, but only for UK residents.

InsideTracker also offers free worldwide shipping, but just for the at-home DNA tests and you’re responsible for the cost of returning your samples. Blood testing is only available in the US via lab locations (with some exceptions) and Canada via mobile blood draw.

You will also need to pay for shipping for SelfDecode, but it does ship all over the world. Living DNA has the most expensive shipping, charging almost $40 for express delivery.

Vitl offers tailored supplement packages to improve your vitamin levels, but be careful, you may be able to purchase similar products cheaper elsewhere. Also, you should be aware that SelfDecode requires you to subscribe to a yearly or lifetime subscription to receive health reports. If you subscribe for just a year, you only get five reports for free, any others must be paid for.

Everlywell, LetsGetChecked, and InsideTracker accept payments via Flexible Savings Accounts/Health Savings Accounts. This could save you on testing costs, but you should talk to your insurance provider before ordering.

How Accurate Are Vitamin B12 Tests?

Although it is important to remember no test is 100% accurate, B12 blood tests tend to be very accurate at measuring your current levels of the vitamin. This can tell you if your levels of B12 are within the normal range and if dietary and lifestyle changes should be made.

DNA vitamin B12 tests are slightly different. As opposed to measuring current levels of B12, they analyze your DNA for the genetic variants that can affect the absorption and metabolism of the vitamin. While DNA tests are accurate and identifying these variants, the presence of them only indicates a predisposition to vitamin B12 deficiency, it is certainly not definitive.

To improve the accuracy of your blood and DNA Vitamin B12 tests, ensure the quality of the samples you provide, by following the instructions correctly. Not doing so may result in your sample being contaminated, and therefore, unusable.

What Will the Results From a Vitamin B12 Test Tell Me?

A blood test will tell you your current level of vitamin B12 and if they are within the normal range, plus dietary advice to help optimize your levels. A DNA test will tell you if your genetic makeup predisposes you to a vitamin B12 deficiency. However, just because you have a genetic predisposition doesn’t mean you will develop a B12 deficiency.

Remember, none of the blood or DNA tests on this list can diagnose a vitamin B12 deficiency or any other health condition. While a blood test gives you a good indicator of your current B12 levels and a DNA test an idea of your genetic predisposition to a deficiency, you should still visit your health care provider for an official diagnosis and appropriate treatment.

How Do the Top Picks Compete on Price?

Vitl offers both the cheapest blood and DNA vitamin B12 tests, which cost less than $80 and included in the price is an analysis of numerous vitamins. You also get free delivery within the UK and personalized nutrition advice, furthering its value for money.

The blood tests offered by LetsGetChecked and Everlywell are also priced at just $89, as they test an individual biomarker (or three in Everlywell’s case). Plus, an option to subscribe to regular testing with LetsGetChecked or an Everlywell membership, will save money on Vitamin B12 and other tests.

SelfDecode is the cheapest of the remaining DNA tests at just $90, however, you will need to pay for a membership if you want to access health reports. Although, you can use existing DNA data from another provider with your membership.

The DNA tests from Living DNA and GenePlanet are similarly priced, and although they are more expensive than blood tests, you do get a lot of additional insights for your money, as well as personalized recommendations to improve your health and wellness.

InsideTracker is by far the most expensive, with the cheapest option offering B12 analysis just under $400. B12 is just one of the biomarkers measured in this test, with many others associated with health and fitness analyzed.

Which Is the Best At-Home Vitamin B12 Test?

Which test you should choose depends on whether you want to know your predisposition to deficiency or your current levels of vitamin B12. It also depends on whether you’re interested in additional nutrition, predisposition, or health insights.

LetsGetChecked andEverlywellprovide the best blood tests for measuring your current levels of vitamin B12, with a fast turnaround for results and consultations offered.

Living DNA is the best value-for-money DNA test that gives insights into your predisposition for vitamin B12 and so much more. Plus, you get excellent personalized dietary and lifestyle advice that will help you optimize your levels and improve your overall health.

If you want to take the complications out of boosting your levels of vitamin B12, as well as other micronutrients, you may be interested in Vitl and it’s tailored supplement subscriptions.

At-Home Vitamin B12 Test Comparison

DNA or Blood Test Physician/Nurse Consultation Dietary Advice Time to Results Starting Price
LetsGetChecked Blood 2-5 days $89.00
Everlywell Blood 2-5 days $89.00
Living DNA DNA 6-8 weeks SGD169.30
SelfDecode DNA 6-8 weeks SGD118.11
Vitl Both 2-4 weeks SGD98.36
InsideTracker Blood 5-7 days SGD510.52
GenePlanet DNA 2-4 weeks SGD152.24

The Bottom Line – Discover More about Your B12 Levels & Predispositions

All the vitamin B12 tests on this list are great choices, with options for testing your predispositions to a deficiency or if your current levels are within the normal range.

If you’re more interested in learning about how your genes may affect your ability to metabolize vitamin B12, choose Living DNA for information about your predispositions and actionable insights.

For monitoring your current vitamin B12 levels, LetsGetChecked offers a discount for regular testing. Or you could sign up for an Everlywell membership and save on a health test every month.

InsideTrackeror SelfDecode are good options if you want more detailed health insights on more than just vitamin B12, as well as extensive personalized recommendations to help you towards a healthier lifestyle.

Best Vitamin B12 Tests in 2023


What are the symptoms of vitamin B12 deficiency?

Vitamin B12 plays an important role in neurological function and maintaining a healthy nervous system, as well as producing DNA and generating red blood cells. It is also an essential micronutrient during pregnancy. Symptoms of a deficiency include:

  • Fatigue, weakness, and lethargy
  • Joint or muscle pain
  • Numbness or tingling
  • Difficulty walking
  • Irritability, mood changes, and depression
  • Skin issues

What preparations do a vitamin B12 test require?

That depends on the provider, so it’s important to check the instructions carefully. Generally speaking, it’s important to be well-hydrated for a blood test, and you may be asked to fast for a few hours beforehand. If you’re submitting a spit or cheek swab DNA sample, you should not eat, drink, or smoke for thirty minutes before preparing your sample.

Does insurance cover vitamin B12 testing?

It’s a possibility. Everlywell, LetsGetChecked, and InsideTracker accept HSA/FSA payments, whereas many competitors do not. Check with your provider before ordering your test.

How do you interpret the results of a vitamin B12 test?

A blood test will tell you if your vitamin B12 level is in the normal range, and what you can do to improve it if necessary. Low levels of B12 could indicate a larger health issue, such as anemia, whereas elevated levels can be a sign of diabetes or cancer. You should review your results and discuss any symptoms with a medical professional.

Who should consider taking a vitamin B12 test? (and how often?)

Vitamin B12 is found in foods like fish, meat, and dairy, and is not naturally produced by the body. The people at the greatest risk for a deficiency are those with strict diets (vegetarian or vegan) as well as older adults and younger children. It is also important for women who are breastfeeding to have their levels checked, to ensure their babies are getting sufficient nutrients. If you find out that you have a deficiency, you can easily take steps to supplement your diet. If you have an existing condition, it might be a good idea to take a test every couple of months to actively monitor your levels.

About Author
Gemma Davison
Gemma Davison

Gemma is an Applied Biology graduate who has always had an interest in DNA, spending a few years after her degree researching epigenetics. She always keeps up to date with the latest advancements in DNA technology and has even DNA-tested her puppy.

Gemma is an Applied Biology graduate who has always had an interest in DNA, spending a few years after her degree researching epigenetics. She always keeps up to date with the latest advancements in DNA technology and has even DNA-tested her puppy.