by Charlotte Grainger

5 Best At-Home DNA Tests for Health and Wellness in 2024

5 Best At-Home DNA Tests for Health and Wellness in 2024

Exploring your genetic makeup can offer a wealth of insights into your health and wellness. However, the process can be confusing due to the plethora of DNA test kits available, each promising in-depth health insights.

To guide you through this, I’ve evaluated numerous DNA kits, focusing on crucial factors such as the accuracy of results, privacy measures, and detail of health reports. From this, I’ve singled out the best DNA kits tailored toward health and wellness.

My top pick is LetsGetChecked. It stands out with accurate results, strong privacy measures, and comprehensive health reports. It provides detailed insights into genetic predispositions for certain conditions, helping you understand and manage your health better. We’ll go into more detail on why LetsGetChecked leads the pack and other top-performing DNA kits for health and wellness.

Get Started With LetsGetChecked

Short on time? Here are our top picks for at-home health and wellness tests

  • LetsGetChecked – Our top pick because of its affordable individual tests that offer detailed reports on your health; you’ll get your results quickly, and can even get nurse support based on your results. 
  • Everlywell – Cheap tests for male and female health, as well as a large number of individual tests that look into different conditions; fast turnaround, within 2-4 days or less for certain tests. 
  • Self Decode – More than 350 reports on your health and wellness, including meal plans and exercise tips; if you already took a test with Ancestry or 23andMe, you can simply upload those results to get health reports for only $99. 
  • MyToolbox Genomics – Good choice if you want ongoing reports and progress updates on your health and wellness journey, as well as meal and supplement suggestions. 
  • Nebula Genomics – Whole 30X genome sequencing which provides more details and accuracy in health and wellness reports.

See how each test compares | FAQs

Our Best DNA Test Kits for Health and Wellness Reviewed

1. LetsGetChecked – Best For Individual Health & Wellness Tests

  • Huge bank of individual tests available, from Omega 3 levels to thyroid function and colon cancer risk
  • Male and female-specific wellness tests, including hormone levels and fertility
  • Connect your fitness tracker to your LetsGetChecked dashboard to monitor your health
  • Subscribe and get wellness test deliveries every 3 months
  • Results in 2-5 days
Price from$69.00
Our score9

When choosing a testing service for your health and well-being, LetsGetChecked stands out with its extensive range of tests. Covering a wide array of health concerns, from hormones and vitamins to chronic conditions, they allow you to focus on what matters most to you.

LetsGetChecked also offers unmatched convenience with their at-home testing kits. With clear instructions, you can collect your samples from the comfort of your home, avoiding the need for lengthy doctor appointments. This setup makes it easier to regularly monitor your health and stay proactive about your well-being.

And let’s not forget the cherry on top – LetsGetChecked goes personal with your wellness insights. They don’t just hand you generic info. Nope, you get recommendations tailored to your health situation. It’s like having your own personalized guide. This info helped me make smarter choices and actively work on feeling better.

Screen Your Health With LetsGetChecked!

2. Everlywell – Best For Female & Male Hormone Testing

  • Detailed female and male hormone testing, including testosterone, progesterone, and thyroid function
  • More individual health tests and STD kits available
  • Subscription options for ongoing health testing
  • Results in 5 days
Price from$49.00
Our score8.5

Everlywell has loads of health tests available, but it’s probably best for its comprehensive female and male hormone kits.

These tests screen for the most common hormones that affect mood, weight, sleep, sex drive, and more. This includes hormones such as testosterone, progesterone, cortisol, and even FT3 which can affect your thyroid function.

You can also choose from a multitude of other health kits, which include a food sensitivity test, allergy screening, vitamin deficiencies, and ovarian reserve kits. It offers sexual health screening, too, with a number of bundles and individual STD tests, which makes it a great all-rounder.

Everlywell offers a subscription service, so you can sign up to receive your chosen test(s) every month, quarter, or twice a year, based on your needs. You can save the most money if you choose the monthly testing option.

Sample collection methods vary depending on the test you choose, but regardless it’s quick and painless. And it only takes up to 5 days to get your results. Your report includes a list of the different biomarkers tested with high, medium, or low levels, alongside personalized advice to help you with your next steps.

Assess your Hormone Levels with Everlywell!

3. Self Decode – Best For Health & Wellness Report Subscriptions

  • Annual and lifetime subscription service with access to tons of reports
  • Screens for everything from heart health to anxiety levels and carrier status
  • Get personalized advice on lifestyle factors and supplements
  • Upload existing DNA from 23andMe, AncestryDNA, and more
Price from$497.00
Our score9

SelfDecode offers an annual and lifetime subscription service that gives you access to individual health reports.

You have to buy a one-off DNA test, but once you have your raw data, all you need to do is upload it each time you want a new report.

You can learn about your optimal nutrition profile, risk of inflammatory diseases, sleep quality, cardiovascular health, and thyroid function, plus much more. There are kits that assess your levels of anxiety and cognitive function.

SelfDecode also offers some cancer screening tests, particularly for inherited cancers like breast cancer. It takes 6-8 weeks to get your raw DNA from the initial DNA test. Or if you’ve already taken a test with 23andMe, AncestryDNA, Courtagen, and FamilyTreeDNA, you can upload your raw data right away.

You can use your DNA to screen your health with other testing companies, and simply pick the reports you want from SelfDecode to get your personalized health overview.

You get detailed risk assessment information based on every biomarker tested, plus advice on supplements and other lifestyle changes that can help you.

Sign up for SelfDecode & Unlock Your Wellness Reports!

4. MyToolbox Genomics – Best For Monitoring Progress

  • 300+ health reports from 1,000 analyzed genetic markers
  • Personalized reports on digestive, mental, and skin health
  • Discover your biological age
  • Monitor impact of lifestyle changes with epigenetic testing
Price from$99.00
Our score8

From your DNA sample, the health and wellness test from MyToolbox Genomics generates over 300 reports by analyzing 1,000 genetic markers covering 16 traits. Discover your predispositions in digestive, skin, eye, and mental health, as well as how your genes influence weight loss, sleep, immunity, and more.

Your result report includes personalized recommendations to help overcome your predispositions. You’ll get tailor-made diet and supplement advice, plus individual exercise and work-out plans to improve your overall health and wellness.

Upgrade to epigenetics testing and you’ll get lifestyle recommendations to alter your gene expression and with regular testing, you can track your progress. Plus, you’ll get five modifiable aging insights: biological age, eye age, hearing health, memory, and inflammation.

Track Your Progress with MyToolbox Genomics!

5. Nebula Genomics – Best For Whole Genome Sequencing

  • 30 x genome sequencing to uncover all of your DNA
  • Screens for 27 different health and wellness traits
  • Search through tons of sources to learn more about your genetic variants
  • Reports available in 8 weeks
Price from$299.00
Our score9.2

Nebula Genomics offers even deeper insights with 30 x whole-genome sequencing. This means it scans more of your DNA and identifies all of your genetic markers to provide you with a comprehensive health report and raw DNA data that you can take away to explore yourself.

It assesses 27 different health traits, which are arranged into four categories: appearance and hormones, behavior and perception, body and athleticism, and nutrition and diet.

You can learn about factors like your risk of high blood pressure, whether you’re a carrier of genes that can cause hereditary cancers and other health conditions. It can even tell you whether you’re likely to be taller than average or have ‘Jimmy legs’ – a trait that causes you to fidget during your sleep.

Next to each trait, you can see the gene tested and which variant you carry, which makes it simple to understand and research yourself.

You can use the Nebula Genomics exploration tools to learn more about your health with your raw DNA data. It includes a gene analysis tool, variant search tool, and genome browser so you can answer any questions to have about your DNA and nucleic sequence.

The Nebula Genomics test also includes ancestry information, if you’re interested in learning about your mtDNA and YDNA. 

Expect to wait up to 8 weeks for your results. If you choose Nebula, be aware there’s a monthly subscription fee on top of your test cost, or you can pay for lifetime access upfront. If you don’t, you can’t access your results anymore.

Get Whole Genome Sequencing with Nebula Genomics!

How We Tested the Best Health & Wellness Kits

Our team of dedicated wellness experts invested several months in comprehensive testing, extensive research, and thorough comparisons of numerous health tests available in the market. Our goal was to present you with the top recommendations based on our stringent criteria, ensuring you always receive the best value and the most accurate results. Here is a breakdown of what we considered:

  1. Legitimacy – For your trust and safety, we rigorously vetted the legitimacy of each DNA company, removing any that raised questions about their credibility. We initially concentrated on companies with professional websites that inspired confidence, since no one wants to deal with a DNA test provider that seems questionable. Our selection was based on companies whose websites were well-designed and looked professional. Additionally, we verified each company’s reputation through trusted customer reviews. Notably, we found that more than 75% of DNA health and wellness companies did not pass this initial evaluation.
  2. Accuracy of Results –  We prioritize accuracy in the results provided by each DNA test. Our team extensively evaluated the scientific methodologies employed by the testing companies to ensure that their analyses and interpretations were backed by robust scientific evidence. We considered factors such as the comprehensiveness of the genetic markers analyzed, the quality of the laboratory facilities used, and the precision of the reported outcomes. Only tests with a proven track record of delivering accurate and reliable insights made it onto our list.

  3. Data Security and Privacy – Protecting your privacy and data security is of paramount importance to us. We carefully examined each company’s data protection measures, encryption protocols, and adherence to industry standards. Our recommended tests prioritize secure storage and transmission of genetic information. We specifically looked for companies that allow you to maintain control over your data, granting you the choice of how it is stored, used, and shared. Providers that demonstrated a strong commitment to data privacy and employed rigorous security measures earned our recommendation.

  4. Customer Support – We understand the value of reliable customer support throughout your testing experience. Our evaluation included an assessment of the responsiveness, helpfulness, and professionalism of the customer support teams of each DNA testing company. We looked for providers that offer multiple channels of communication, such as live chat, email, and phone support. The inclusion of clear and comprehensive FAQs, user guides, and educational resources also played a role in our assessment. Companies that prioritize exceptional customer support earned higher rankings on our list.

  5. Cost and Value – We recognize the importance of affordability and value for money. Our team considered the pricing structures of each DNA test, evaluating the overall cost in relation to the provided features, accuracy, and additional services offered. We carefully examined the transparency of pricing, ensuring there were no hidden fees or unexpected charges. Our list comprises tests that provide excellent value, offering a balance between affordability and the quality of insights provided.

  6. Ease of Use – We understand the importance of a seamless and user-friendly testing process. Our team assessed the ease of sample collection, the clarity of instructions, and the simplicity of result interpretation. We favored tests that provided intuitive interfaces, clear guidelines, and accessible platforms for accessing and understanding your results. Our recommended tests prioritize a hassle-free experience, making it convenient for users to navigate through the entire testing journey.

How Accurate Are At-home Health & Wellness Tests?

Ensuring the medical reliability of DNA health and wellness tests is crucial to prevent the consequences of following incorrect advice purportedly based on factual data. In preparation for our review, we gathered comprehensive information on our known genetic risks and medical histories. We also conducted various saliva, urine, and blood tests in collaboration with healthcare professionals to serve as a benchmark for assessing the accuracy of DNA tests purchased online.

The DNA health and wellness tests that we recommend showed consistent and reliable results, remaining within an acceptable margin of error compared to our benchmark. We also scrutinized the DNA reports for any unusual similarities that might cast doubt on the reliability of our initial tests, and fortunately, we found no discrepancies.

It’s important to note that the tests we endorse are highly accurate, with some achieving up to 99.9% accuracy. We verified that all participating laboratories are CLIA certified and involve qualified physicians to review the results. However, it is essential to recognize that no test or laboratory can guarantee absolute accuracy, regardless of its credentials or technological sophistication.

Can Customer Service Answer All of Your Questions?

As customers, we deserve a certain level of satisfaction in order to justify paying money to one of these DNA testing companies. If we’re paying money, we want that product to be delivered quickly, correctly, and without issue. And, in the rare event that there is an issue, we need to know that it can be rectified ASAP. So, we made sure every test on this list offers:

  • Easy-to-understand testing procedures and health reports
  • Various support channels (24/7 live chat support is the gold standard)
  • A detailed refund policy if the service hasn’t been delivered correctly

Which Test Gives You the Best Value For Money?

At-home DNA testing isn’t always cheap, so we wanted to make sure you really get your money’s worth with whichever test you choose. From initial test fees and shipping costs, to the detail in your report and on-going support, we looked at everything on offer. And you’re probably wondering which test on this list actually offers the best value of them all.

I’d have to say LetsGetChecked delivers the best value for money. Aside from the fact it has thousands of overwhelmingly positive reviews from customers, it’s also very budget-friendly and comes with the most insightful health report. Remember, though, the best value for you also depends on what you need from your test.

If you’re hoping your health test can identify food intolerances, a kit that screens for heath carrier risks probably won’t fit the bill. That’s why we’ve recommended a varied list of health tests to suit everyone’s needs – and budgets.

Which Health & Wellness DNA Test Should You Choose?

Choosing the right health and wellness test depends on factors like how quickly you want results, the specific health information you’re after, and your budget.

If you need to examine specific health aspects or want gender-specific tests, LetsGetChecked is a good option. It also provides fast results, usually within 2-5 days.

For ongoing health assessments, consider Everlywell. For a monthly fee, you can choose a new test each month, giving you continuous insight into your health. The company also offers specialized hormone tests for males and females.

If your main goal is to improve your diet and fitness while tracking your progress, MyToolbox Genomics is a strong choice. It offers advice on diet and exercise and allows you to monitor how lifestyle changes affect your genes through regular epigenetics testing.

  Specialty Free shipping Free Medical Consultancy Results ETA Starting Price
LetsGetChecked Male and female health testing, and sexual health 2-5 days $69.00
Everlywell Hormone and sexual health testing 5 days $99.00
My Toolbox Genomics Nutrition and fitness 4-6 weeks $199.00
SelfDecode General health and wellness, and behaviors and traits 6-8 weeks $199.00
Nebula Genomics Whole-genome sequencing 8 weeks $299.00

FAQs

What does a health and wellness DNA test tell you?

A health and wellness test can tell you many things, from how your body metabolizes different foods, to whether you carry the genes for certain health conditions. Here are some common things a health and wellness test can tell you:

  • Whether you’re at risk of certain health conditions
  • If you carry the genes for any genetic diseases
  • Your overall nutritional health and optimal diet 
  • Your body’s vitamin and mineral deficiencies 
  • Your personality traits and behaviors

How do you read and interpret the results of a health and wellness DNA test?

Most reports offer a PDF download or online report to interpret your results. Usually, your report includes a list of the biomarkers tested for each aspect of your health alongside your specific genetic variants.  For health conditions or diseases, a report will often tell you your risk level, particularly whether you have a low, medium, or high risk of developing a health condition. Some testing services like LetsGetChecked provide access to a genetic counselor or other professional to help you interpret your results. And others even offer personal health coaching.

Can a health and wellness DNA test determine if you have cancer? 

No. A DNA test can only tell you if you’re genetically at a higher risk of getting cancer than other people in the population. It gives you an indication that you should be taking preventative measures or talking to your doctor about the kinds of cancer that are identified. You should always take your results to your doctor to get diagnosed correctly.

What general medical conditions can health and wellness DNA tests show?

Most DNA tests screen for risks associated with various types of cancer and heart disease, along with degenerative disorders like Alzheimer’s and Parkinson’s. Many will also tell you if you carry a certain genetic marker that could be passed down to your children.

What common genetic wellness traits can you find out?

Your DNA contains a lot of information about things that make you unique. As well as physical features like hair thickness and skin type, DNA tests can predict the most obscure behaviors, such as your favorite ice cream flavor or whether you have a fear of heights. You can also learn about your likelihood of developing mental health conditions, such as anxiety or depression, and your overall cognitive ability.

What are carrier status reports? 

A carrier status report tells you if you carry specific genetic markers for conditions that could be passed on to your children if your partner has the same gene variants.

What is a genetic predisposition? 

A genetic predisposition means your DNA makes it more likely that you will develop a specific disease (or diseases), based on environmental conditions. It doesn’t mean you’ll definitely develop the disease, but it does mean you are more likely to than most people.

What is cellular aging?

Cellular aging refers to your cells’ reduced ability to resist stress and other cellular damage over time. The DNA in your cells can get damaged when the telomeres that cap the ends of your chromosomes get shorter, just as your shoelaces start to fray when the plastic caps on their ends wear away.

Can a health and wellness DNA test tell your age?

The length of the telomeres that cap off your chromosomes can be measured to give an indication of your “biological age,” which may well be different from your chronological age (i.e., how long you have been alive).  

Should you share your health and wellness DNA report with a doctor? 

Yes. In general, it’s a good idea to share anything related to your health with your doctor. Sharing your results is especially important if you are genetically predisposed to certain conditions or if your DNA suggests that you could react adversely to some pharmaceuticals. Your doctor will be able to arrange an official medical diagnosis for any health conditions you’re identified as being at high risk of. They can also coordinate your care effectively and make sure you receive the right treatment.

We rank vendors based on rigorous testing and research, but also take into account your feedback and our commercial agreements with providers. This page contains affiliate links. Learn more.
About Author
Charlotte Grainger
Charlotte Grainger
Charlotte Grainger

I am freelance journalist and content writer living in Sheffield. I hold a BA in Journalism and an MA in Creative Writing. When I'm not working, you can find me at the gym or hanging out with my cat, Harry.

I am freelance journalist and content writer living in Sheffield. I hold a BA in Journalism and an MA in Creative Writing. When I'm not working, you can find me at the gym or hanging out with my cat, Harry.